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08/26/2023
An exhaustive ADDIS principle for online FWER control
In this paper we consider online multiple testing with familywise error ...
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04/06/2023
Optimal allocation strategies in platform trials
Platform trials are randomized clinical trials that allow simultaneous c...
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02/24/2023
NCC: An R-package for analysis and simulation of platform trials with non-concurrent controls
Platform trials evaluate the efficacy of multiple treatments, allowing f...
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01/27/2023
An Adaptive-Discard-Graph for online error control
In recent years, graphical multiple testing procedures have gained popul...
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11/21/2022
The Online Closure Principle
The closure principle is fundamental in multiple testing and has been us...
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11/17/2022
On the use of non-concurrent controls in platform trials: A scoping review
Platform trials gained popularity during the last few years as they incr...
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11/04/2022
Design of Trials with Composite Endpoints with the R Package CompAREdesign
Composite endpoints are widely used as primary endpoints in clinical tri...
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06/20/2022
Adaptive clinical trial designs with blinded selection of binary composite endpoints and sample size reassessment
For randomized clinical trials where a single, primary, binary endpoint ...
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12/13/2021
On model-based time trend adjustments in platform trials with non-concurrent controls
Platform trials can evaluate the efficacy of several treatments compared...
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08/29/2020
Design of phase III trials with long-term survival outcomes based on short-term binary results
Pathologic complete response (pCR) is a common primary endpoint for a ph...
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02/04/2020
A general class of two-sample statistics for binary and time-to-event outcomes
We propose a class of two-sample statistics for testing the equality of ...
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01/10/2020
Decision tool and Sample Size Calculator for Composite Endpoints
Summary points: - This article considers the combination of two binary...
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07/03/2018