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04/06/2023
Optimal allocation strategies in platform trials
Platform trials are randomized clinical trials that allow simultaneous c...
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10/12/2022
Designing an exploratory phase 2b platform trial in NASH with correlated, co-primary binary endpoints
Non-alcoholic steatohepatitis (NASH), an inflammatory and more progressi...
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04/12/2022
Familywise error rate control for block response-adaptive randomization
Response-adaptive randomization allows the probabilities of allocating p...
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02/04/2022
CohortPlat: Simulation of cohort platform trials investigating combination therapies
Platform trials have gained a lot of attention recently as a possible re...
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12/13/2021
On model-based time trend adjustments in platform trials with non-concurrent controls
Platform trials can evaluate the efficacy of several treatments compared...
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08/04/2021
Geometric approaches to assessing the numerical feasibility for conducting matching-adjusted indirect comparisons
We discuss how to handle matching-adjusted indirect comparison (MAIC) fr...
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03/17/2021
Decision rules for identifying combination therapies in open-entry, randomized controlled platform trials
The design and conduct of platform trials have become increasingly popul...
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12/07/2020
Connecting Instrumental Variable methods for causal inference to the Estimand Framework
Instrumental Variables (IV) methods are gaining increasing prominence in...
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08/13/2019
Blinded sample size re-estimation in equivalence testing
This paper investigates type I error violations that occur when blinded ...
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05/10/2019