Microscopy Image Restoration using Deep Learning on W2S

04/22/2020
by   Martin Chatton, et al.
78

We leverage deep learning techniques to jointly denoise and super-resolve biomedical images acquired with fluorescence microscopy. We develop a deep learning algorithm based on the networks and method described in the recent W2S paper to solve a joint denoising and super-resolution problem. Specifically, we address the restoration of SIM images from widefield images. Our TensorFlow model is trained on the W2S dataset of cell images and is made accessible online in this repository: https://github.com/mchatton/w2s-tensorflow. On test images, the model shows a visually-convincing denoising and increases the resolution by a factor of two compared to the input image. For a 512 × 512 image, the inference takes less than 1 second on a Titan X GPU and about 15 seconds on a common CPU. We further present the results of different variations of losses used in training.

READ FULL TEXT

page 2

page 5

page 7

page 8

page 9

page 10

page 11

page 12

research
03/12/2020

W2S: A Joint Denoising and Super-Resolution Dataset

Denoising and super-resolution (SR) are fundamental tasks in imaging. Th...
research
03/07/2021

Deep learning-based super-resolution fluorescence microscopy on small datasets

Fluorescence microscopy has enabled a dramatic development in modern bio...
research
03/18/2019

PZnet: Efficient 3D ConvNet Inference on Manycore CPUs

Convolutional nets have been shown to achieve state-of-the-art accuracy ...
research
10/12/2018

Cryo-CARE: Content-Aware Image Restoration for Cryo-Transmission Electron Microscopy Data

Multiple approaches to use deep learning for image restoration have rece...
research
05/20/2018

DLBI: Deep learning guided Bayesian inference for structure reconstruction of super-resolution fluorescence microscopy

Super-resolution fluorescence microscopy, with a resolution beyond the d...
research
08/29/2018

Autoencoders, Kernels, and Multilayer Perceptrons for Electron Micrograph Restoration and Compression

We present 14 autoencoders, 15 kernels and 14 multilayer perceptrons for...
research
11/12/2019

Scientific Image Restoration Anywhere

The use of deep learning models within scientific experimental facilitie...

Please sign up or login with your details

Forgot password? Click here to reset