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08/24/2023
Estimating hypothetical estimands with causal inference and missing data estimators in a diabetes trial
The recently published ICH E9 addendum on estimands in clinical trials p...
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01/27/2023
G-formula for causal inference via multiple imputation
G-formula is a popular approach for estimating treatment or exposure eff...
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09/23/2022
Weighted hazard ratio estimation for delayed and diminishing treatment effect
Non-proportional hazards (NPH) have been observed in confirmatory clinic...
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09/23/2021
Reference-based imputation methods based on conditional mean imputation
Clinical trials with longitudinal outcomes typically include missing dat...
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07/09/2021
Hypothetical estimands in clinical trials: a unification of causal inference and missing data methods
The ICH E9 addendum introduces the term intercurrent event to refer to e...
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04/28/2021
Reference based multiple imputation – what is the right variance and how to estimate it
Reference based multiple imputation methods have become popular for hand...
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11/22/2019
Bootstrap Inference for Multiple Imputation under Uncongeniality and Misspecification
Multiple imputation has become one of the most popular approaches for ha...
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10/14/2019
Measurement error as a missing data problem
This article focuses on measurement error in covariates in regression an...
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05/21/2019