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07/06/2022
A flexible model-based framework for robust estimation of mutational signatures
Somatic mutations in cancer can be viewed as a mixture distribution of s...
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06/07/2022
Model selection for robust learning of mutational signatures using Negative Binomial non-negative matrix factorization
The spectrum of mutations in a collection of cancer genomes can be descr...
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01/19/2021
A sampling algorithm to compute the set of feasible solutions for non-negative matrix factorization with an arbitrary rank
Non-negative Matrix Factorization (NMF) is a useful method to extract fe...
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01/13/2021
Multivariate phase-type theory for the site frequency spectrum
Linear functions of the site frequency spectrum (SFS) play a major role ...
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06/04/2018