varTestnlme: Variance Components Testing in Linear and Nonlinear Mixed-effects Models

07/09/2020
by   Charlotte Baey, et al.
0

The issue of variance components testing arises naturally when building mixed-effects models, to decide which effects should be modeled as fixed or random. While tests for fixed effects are available in R for models fitted with lme4, tools are missing when it comes to random effects. The varTestnlme package for R aims at filling this gap. It allows to test whether any subset of the variances and covariances are equal to zero using likelihood ratio tests. It also offers the possibility to test simultaneously for fixed effects and variance components. It can be used for linear, generalized linear or nonlinear mixed-effects models fitted via lme4, nlme or saemix. Theoretical properties of the used likelihood ratio test are recalled and examples based on different real datasets using different mixed models are provided.

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