Partial Correlations in Compositional Data Analysis

04/20/2019
by   Ionas Erb, et al.
0

Partial correlations quantify linear association between two variables adjusting for the influence of the remaining variables. They form the backbone for graphical models and are readily obtained from the inverse of the covariance matrix. For compositional data, the covariance structure is specified from log ratios of variables, so unless we try to "open" the data via a normalization, this implies changes in the definition and interpretation of partial correlations. In the present work, we elucidate how results derived by Aitchison (1986) lead to a natural definition of partial correlation that has a number of advantages over current measures of association. For this, we show that the residuals of log-ratios between a variable with a reference, when adjusting for all remaining variables including the reference, are reference-independent. Since the reference itself can be controlled for, correlations between residuals are defined for the variables directly without the necessity to recur to ratios except when specifying which variables are partialled out. Thus, perhaps surprisingly, partial correlations do not have the problems commonly found with measures of pairwise association on compositional data. They are well-defined between two variables, are properly scaled, and allow for negative association. By design, they are subcompositionally incoherent, but they share this property with conventional partial correlations (where results change when adjusting for the influence of fewer variables). We discuss the equivalence with normalization-based approaches whenever the normalizing variables are controlled for. We also discuss the partial variances and correlations we obtain from a previously studied data set of Roman glass cups.

READ FULL TEXT

page 1

page 2

page 3

page 4

research
12/01/2022

Compositional Covariance Shrinkage and Regularised Partial Correlations

We propose an estimation procedure for covariation in wide compositional...
research
07/03/2022

Reference-Invariant Inverse Covariance Estimation with Application to Microbial Network Recovery

The interactions between microbial taxa in microbiome data has been unde...
research
12/21/2020

Towards Conditional Path Analysis

We extend path analysis by giving sufficient conditions for computing th...
research
01/25/2022

Extending compositional data analysis from a graph signal processing perspective

Traditional methods for the analysis of compositional data consider the ...
research
07/30/2020

Covariance estimation with nonnegative partial correlations

We study the problem of high-dimensional covariance estimation under the...
research
07/13/2018

Improved Methods for Making Inferences About Multiple Skipped Correlations

A skipped correlation has the advantage of dealing with outliers in a ma...
research
03/17/2019

On the Computation and Applications of Large Dense Partial Correlation Networks

While sparse inverse covariance matrices are very popular for modeling n...

Please sign up or login with your details

Forgot password? Click here to reset