Low-Cost and High-Throughput Testing of COVID-19 Viruses and Antibodies via Compressed Sensing: System Concepts and Computational Experiments

by   Jirong Yi, et al.

Coronavirus disease 2019 (COVID-19) is an ongoing pandemic infectious disease outbreak that has significantly harmed and threatened the health and lives of millions or even billions of people. COVID-19 has also negatively impacted the social and economic activities of many countries significantly. With no approved vaccine available at this moment, extensive testing of COVID-19 viruses in people are essential for disease diagnosis, virus spread confinement, contact tracing, and determining right conditions for people to return to normal economic activities. Identifying people who have antibodies for COVID-19 can also help select persons who are suitable for undertaking certain essential activities or returning to workforce. However, the throughputs of current testing technologies for COVID-19 viruses and antibodies are often quite limited, which are not sufficient for dealing with COVID-19 viruses' anticipated fast oscillating waves of spread affecting a significant portion of the earth's population. In this paper, we propose to use compressed sensing (group testing can be seen as a special case of compressed sensing when it is applied to COVID-19 detection) to achieve high-throughput rapid testing of COVID-19 viruses and antibodies, which can potentially provide tens or even more folds of speedup compared with current testing technologies. The proposed compressed sensing system for high-throughput testing can utilize expander graph based compressed sensing matrices developed by us <cit.>.


page 1

page 2

page 3

page 4


Practical High-Throughput, Non-Adaptive and Noise-Robust SARS-CoV-2 Testing

We propose a compressed sensing-based testing approach with a practical ...

Randomness and isometries in echo state networks and compressed sensing

Although largely different concepts, echo state networks and compressed ...

Dynamic Compressed Sensing for Real-Time Tomographic Reconstruction

Electron tomography has achieved higher resolution and quality at reduce...

On Accelerated Testing for COVID-19 Using Group Testing

COVID-19 has resulted in a global health crisis that may become even mor...

"COVID-19 was a FIFA conspiracy #curropt": An Investigation into the Viral Spread of COVID-19 Misinformation

The outbreak of the infectious and fatal disease COVID-19 has revealed t...

CovidChain: An Anonymity Preserving Blockchain Based Framework for Protection Against Covid-19

Today, the entire world is facing incredible health and economic challen...

Surveillance Testing for Rapid Detection of Outbreaks in Facilities

This paper develops an agent-based disease spread model on a contact net...

Please sign up or login with your details

Forgot password? Click here to reset