Learn like a Pathologist: Curriculum Learning by Annotator Agreement for Histopathology Image Classification

09/29/2020
by   Jerry Wei, et al.
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Applying curriculum learning requires both a range of difficulty in data and a method for determining the difficulty of examples. In many tasks, however, satisfying these requirements can be a formidable challenge. In this paper, we contend that histopathology image classification is a compelling use case for curriculum learning. Based on the nature of histopathology images, a range of difficulty inherently exists among examples, and, since medical datasets are often labeled by multiple annotators, annotator agreement can be used as a natural proxy for the difficulty of a given example. Hence, we propose a simple curriculum learning method that trains on progressively-harder images as determined by annotator agreement. We evaluate our hypothesis on the challenging and clinically-important task of colorectal polyp classification. Whereas vanilla training achieves an AUC of 83.7 trained with our proposed curriculum learning approach achieves an AUC of 88.2 more creatively and rigorously when choosing contexts for applying curriculum learning.

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