Kernel regression for cause-specific hazard models with time-dependent coefficients

07/23/2021

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by   Xiaomeng Qi, et al.

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Competing risk data appear widely in modern biomedical research. Cause-specific hazard models are often used to deal with competing risk data in the past two decades. There is no current study on the kernel likelihood method for the cause-specific hazard model with time-varying coefficients. We propose to use the local partial log-likelihood approach for nonparametric time-varying coefficient estimation. Simulation studies demonstrate that our proposed nonparametric kernel estimator has a good performance under assumed finite sample settings. Finally, we apply the proposed method to analyze a diabetes dialysis study with competing death causes.