DeepAI AI Chat
Log In Sign Up

Identification of relevant diffusion MRI metrics impacting cognitive functions using a novel feature selection method

by   Tongda Xu, et al.
NYU college
NYU Langone Medical Center

Mild Traumatic Brain Injury (mTBI) is a significant public health problem. The most troubling symptoms after mTBI are cognitive complaints. Studies show measurable differences between patients with mTBI and healthy controls with respect to tissue microstructure using diffusion MRI. However, it remains unclear which diffusion measures are the most informative with regard to cognitive functions in both the healthy state as well as after injury. In this study, we use diffusion MRI to formulate a predictive model for performance on working memory based on the most relevant MRI features. The key challenge is to identify relevant features over a large feature space with high accuracy in an efficient manner. To tackle this challenge, we propose a novel improvement of the best first search approach with crossover operators inspired by genetic algorithm. Compared against other heuristic feature selection algorithms, the proposed method achieves significantly more accurate predictions and yields clinically interpretable selected features.


Predicting conversion of mild cognitive impairment to Alzheimer's disease

Alzheimer's disease (AD) is the most common age-related dementia. Mild c...

Patched Diffusion Models for Unsupervised Anomaly Detection in Brain MRI

The use of supervised deep learning techniques to detect pathologies in ...

Cardiac Cohort Classification based on Morphologic and Hemodynamic Parameters extracted from 4D PC-MRI Data

An accurate assessment of the cardiovascular system and prediction of ca...

MRI correlates of chronic symptoms in mild traumatic brain injury

Veterans with mild traumatic brain injury (mTBI) have reported auditory ...

MTBI Identification From Diffusion MR Images Using Bag of Adversarial Visual Features

In this work, we propose bag of adversarial features (BAF) for identifyi...

A Radiomics Approach to Computer-Aided Diagnosis with Cardiac Cine-MRI

Use expert visualization or conventional clinical indices can lack accur...