Hyper-Pairing Network for Multi-Phase Pancreatic Ductal Adenocarcinoma Segmentation

09/03/2019

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by   Yuyin Zhou, et al.

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Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers with an overall five-year survival rate of 8 PDAC, pancreatic dual-phase imaging is recommended for better diagnosis of pancreatic disease. In this study, we aim at enhancing PDAC automatic segmentation by integrating multi-phase information (i.e., arterial phase and venous phase). To this end, we present Hyper-Pairing Network (HPN), a 3D fully convolution neural network which effectively integrates information from different phases. The proposed approach consists of a dual path network where the two parallel streams are interconnected with hyper-connections for intensive information exchange. Additionally, a pairing loss is added to encourage the commonality between high-level feature representations of different phases. Compared to prior arts which use single phase data, HPN reports a significant improvement up to 7.73 of DSC.