Gastric histopathology image segmentation using a hierarchical conditional random field

by   Changhao Sun, et al.

In this paper, a Hierarchical Conditional Random Field (HCRF) model based Gastric Histopathology Image Segmentation (GHIS) method is proposed, which can localize abnormal (cancer) regions in gastric histopathology images obtained by optical microscope to assist histopathologists in medical work. First, to obtain pixel-level segmentation information, we retrain a Convolutional Neural Network (CNN) to build up our pixel-level potentials. Then, in order to obtain abundant spatial segmentation information in patch-level, we fine-tune another three CNNs to build up our patch-level potentials. Thirdly, based on the pixel- and patch-level potentials, our HCRF model is structured. Finally, graph-based post-processing is applied to further improve our segmentation performance. In the experiment, a segmentation accuracy of 78.91 and Eosin (H E) stained gastric histopathological dataset with 560 images, showing the effectiveness and future potential of the proposed GHIS method.



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