FastCPH: Efficient Survival Analysis for Neural Networks

08/21/2022
by   Xuelin Yang, et al.
8

The Cox proportional hazards model is a canonical method in survival analysis for prediction of the life expectancy of a patient given clinical or genetic covariates – it is a linear model in its original form. In recent years, several methods have been proposed to generalize the Cox model to neural networks, but none of these are both numerically correct and computationally efficient. We propose FastCPH, a new method that runs in linear time and supports both the standard Breslow and Efron methods for tied events. We also demonstrate the performance of FastCPH combined with LassoNet, a neural network that provides interpretability through feature sparsity, on survival datasets. The final procedure is efficient, selects useful covariates and outperforms existing CoxPH approaches.

READ FULL TEXT
research
05/18/2021

Neural networks to predict survival from RNA-seq data in oncology

Survival analysis consists of studying the elapsed time until an event o...
research
06/14/2022

Neural interval-censored Cox regression with feature selection

The classical Cox model emerged in 1972 promoting breakthroughs in how p...
research
06/02/2016

DeepSurv: Personalized Treatment Recommender System Using A Cox Proportional Hazards Deep Neural Network

Medical practitioners use survival models to explore and understand the ...
research
05/14/2019

Nonlinear Semi-Parametric Models for Survival Analysis

Semi-parametric survival analysis methods like the Cox Proportional Haza...
research
05/04/2018

Estimation of Extreme Survival Probabilities with Cox Model

We propose an extension of the regular Cox's proportional hazards model ...
research
03/18/2020

SurvLIME: A method for explaining machine learning survival models

A new method called SurvLIME for explaining machine learning survival mo...
research
03/23/2021

BoXHED 2.0: Scalable boosting of functional data in survival analysis

Modern applications of survival analysis increasingly involve time-depen...

Please sign up or login with your details

Forgot password? Click here to reset