Bounding Disease Prevalence by Bounding Selectivity and Accuracy of Tests: The Case of COVID-19

08/14/2020
by   Jörg Stoye, et al.
0

I propose novel partial identification bounds on disease prevalence from information on test rate and test yield. The approach broadly follows recent work by <cit.> on COVID-19, but starts from user-specified bounds on (i) test accuracy, in particular sensitivity, (ii) the extent to which tests are targeted, formalized as restriction on the effect of true status on the odds ratio of getting tested and thereby embeddable in logit specifications. The motivating application is to the COVID-19 pandemic but the strategy may also be useful elsewhere. Evaluated on data from the pandemic's early stage, even the weakest of the novel bounds are reasonably informative. For example, they place the infection fatality rate for Italy well above the one of influenza by mid-April.

READ FULL TEXT

page 1

page 2

page 3

page 4

research
05/18/2021

Pooled testing and its applications in the COVID-19 pandemic

When testing for a disease such as COVID-19, the standard method is indi...
research
03/02/2022

Partial Likelihood Thompson Sampling

We consider the problem of deciding how best to target and prioritize ex...
research
11/29/2020

Exact Inference for Disease Prevalence Based on a Test with Unknown Specificity and Sensitivity

To make informative public policy decisions in battling the ongoing COVI...
research
06/29/2020

Estimation of Covid-19 Prevalence from Serology Tests: A Partial Identification Approach

We propose a partial identification method for estimating disease preval...
research
04/01/2022

Measuring Diagnostic Test Performance Using Imperfect Reference Tests: A Partial Identification Approach

Diagnostic tests are almost never perfect. Studies quantifying their per...
research
09/29/2021

Incorporating global dynamics to improve the accuracy of disease models: Example of a COVID-19 SIR model

Mathematical models of infectious diseases exhibit robust dynamics such ...
research
12/13/2020

Invariant Points on the Screening Plane: a Geometric Definition of the Likelihood Ratio (LR+)

From the fundamental theorem of screening we obtain the following mathem...

Please sign up or login with your details

Forgot password? Click here to reset