Bounding Disease Prevalence by Bounding Selectivity and Accuracy of Tests: The Case of COVID-19

08/14/2020
by   Jörg Stoye, et al.
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I propose novel partial identification bounds on disease prevalence from information on test rate and test yield. The approach broadly follows recent work by <cit.> on COVID-19, but starts from user-specified bounds on (i) test accuracy, in particular sensitivity, (ii) the extent to which tests are targeted, formalized as restriction on the effect of true status on the odds ratio of getting tested and thereby embeddable in logit specifications. The motivating application is to the COVID-19 pandemic but the strategy may also be useful elsewhere. Evaluated on data from the pandemic's early stage, even the weakest of the novel bounds are reasonably informative. For example, they place the infection fatality rate for Italy well above the one of influenza by mid-April.

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