Asymptotic based bootstrap approach for matched pairs with missingness in a single-arm

12/10/2019
by   Lubna Amro, et al.
0

The issue of missing values is an arising difficulty when dealing with paired data. Several test procedures are developed in the literature to tackle this problem. Some of them are even robust under deviations and control type-I error quite accurately. However, most these methods are not applicable when missing values are present only in a single arm. For this case, we provide asymptotic correct resampling tests that are robust under heteroscedasticity and skewed distributions. The tests are based on a clever restructuring of all observed information in a quadratic form-type test statistic. An extensive simulation study is conducted exemplifying the tests for finite sample sizes under different missingness mechanisms. In addition, an illustrative data example based on a breast cancer gene study is analyzed.

READ FULL TEXT

page 1

page 2

page 3

page 4

research
06/18/2018

A cautionary tale on using imputation methods for inference in matched pairs design

Imputation procedures in biomedical fields have turned into statistical ...
research
01/08/2020

Tests for detecting risk equivalent portfolios

The aim of this paper is the development of consistent tests for the com...
research
08/03/2020

A Robust Spearman Correlation Coefficient Permutation Test

In this work, we show that Spearman's correlation coefficient test about...
research
01/26/2018

Multiplication-Combination Tests for Incomplete Paired Data

We consider statistical procedures for hypothesis testing of real valued...
research
10/24/2022

E-Valuating Classifier Two-Sample Tests

We propose E-C2ST, a classifier two-sample test for high-dimensional dat...
research
10/25/2021

Weighted Mean Difference Statistics for Paired Data in Presence of Missing Values

Missing data is a common issue in many biomedical studies. Under a paire...
research
01/15/2020

Valid p-Values and Expectations of p-Values Revisited

A storm of favorable or critical publications regarding p-values-based p...

Please sign up or login with your details

Forgot password? Click here to reset