A training-free recursive multiresolution framework for diffeomorphic deformable image registration

by   Ameneh Sheikhjafari, et al.

Diffeomorphic deformable image registration is one of the crucial tasks in medical image analysis, which aims to find a unique transformation while preserving the topology and invertibility of the transformation. Deep convolutional neural networks (CNNs) have yielded well-suited approaches for image registration by learning the transformation priors from a large dataset. The improvement in the performance of these methods is related to their ability to learn information from several sample medical images that are difficult to obtain and bias the framework to the specific domain of data. In this paper, we propose a novel diffeomorphic training-free approach; this is built upon the principle of an ordinary differential equation. Our formulation yields an Euler integration type recursive scheme to estimate the changes of spatial transformations between the fixed and the moving image pyramids at different resolutions. The proposed architecture is simple in design. The moving image is warped successively at each resolution and finally aligned to the fixed image; this procedure is recursive in a way that at each resolution, a fully convolutional network (FCN) models a progressive change of deformation for the current warped image. The entire system is end-to-end and optimized for each pair of images from scratch. In comparison to learning-based methods, the proposed method neither requires a dedicated training set nor suffers from any training bias. We evaluate our method on three cardiac image datasets. The evaluation results demonstrate that the proposed method achieves state-of-the-art registration accuracy while maintaining desirable diffeomorphic properties.


page 6

page 11

page 13


Recursive Cascaded Networks for Unsupervised Medical Image Registration

We present recursive cascaded networks, a general architecture that enab...

Deformable Medical Image Registration Using a Randomly-Initialized CNN as Regularization Prior

We present deformable unsupervised medical image registration using a ra...

Ordinary Differential Equation and Complex Matrix Exponential for Multi-resolution Image Registration

Autograd-based software packages have recently renewed interest in image...

MDReg-Net: Multi-resolution diffeomorphic image registration using fully convolutional networks with deep self-supervision

We present a diffeomorphic image registration algorithm to learn spatial...

ORRN: An ODE-based Recursive Registration Network for Deformable Respiratory Motion Estimation with Lung 4DCT Images

Deformable Image Registration (DIR) plays a significant role in quantify...

Dilated FCN for Multi-Agent 2D/3D Medical Image Registration

2D/3D image registration to align a 3D volume and 2D X-ray images is a c...

Non-Rigid Image Registration Using Self-Supervised Fully Convolutional Networks without Training Data

A novel non-rigid image registration algorithm is built upon fully convo...

Please sign up or login with your details

Forgot password? Click here to reset