A Semantic Cross-Species Derived Data Management Application

by   David B. Keator, et al.

Managing dynamic information in large multi-site, multi-species, and multi-discipline consortia is a challenging task for data management applications. Often in academic research studies the goals for informatics teams are to build applications that provide extract-transform-load (ETL) functionality to archive and catalog source data that has been collected by the research teams. In consortia that cross species and methodological or scientific domains, building interfaces that supply data in a usable fashion and make intuitive sense to scientists from dramatically different backgrounds increases the complexity for developers. Further, reusing source data from outside one's scientific domain is fraught with ambiguities in understanding the data types, analysis methodologies, and how to combine the data with those from other research teams. We report on the design, implementation, and performance of a semantic data management application to support the NIMH funded Conte Center at the University of California, Irvine. The Center is testing a theory of the consequences of "fragmented" (unpredictable, high entropy) early-life experiences on adolescent cognitive and emotional outcomes in both humans and rodents. It employs cross-species neuroimaging, epigenomic, molecular, and neuroanatomical approaches in humans and rodents to assess the potential consequences of fragmented unpredictable experience on brain structure and circuitry. To address this multi-technology, multi-species approach, the system uses semantic web techniques based on the Neuroimaging Data Model (NIDM) to facilitate data ETL functionality. We find this approach enables a low-cost, easy to maintain, and semantically meaningful information management system, enabling the diverse research teams to access and use the data.


page 5

page 7

page 8

page 10

page 11


Conversational AI: The Science Behind the Alexa Prize

Conversational agents are exploding in popularity. However, much work re...

Deep learning powered real-time identification of insects using citizen science data

Insect-pests significantly impact global agricultural productivity and q...

Wildbook: Crowdsourcing, computer vision, and data science for conservation

Photographs, taken by field scientists, tourists, automated cameras, and...

Testing Reviewer Suggestions Derived from Bibliometric Specialty Approximations in Real Research Evaluations

Many contemporary research funding instruments and research policies aim...

SemEval-2010 Task 8: Multi-Way Classification of Semantic Relations Between Pairs of Nominals

In response to the continuing research interest in computational semanti...

The I-ADOPT Interoperability Framework for FAIRer data descriptions of biodiversity

Biodiversity, the variation within and between species and ecosystems, i...

Please sign up or login with your details

Forgot password? Click here to reset