A New 3D Segmentation Methodology for Lumbar Vertebral Bodies for the Measurement of BMD and Geometry

05/19/2017

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by   Andre Mastmeyer, et al.

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In this paper a new technique is presented that extracts the geometry of lumbar vertebral bodies from spiral CT scans. Our new multi-step segmentation approach yields highly accurate and precise measurement of the bone mineral density (BMD) in different volumes of interest which are defined relative to a local anatomical coordinate systems. The approach also enables the analysis of the geometry of the relevant vertebrae. Intra- and inter operator precision for segmentation, BMD measurement and position of the coordinate system are below 1.5 volume in phantom data. The long-term goal of the approach is to improve fracture prediction in osteoporosis.