A Memristor-Inspired Computation for Epileptiform Signals in Spheroids

07/10/2023

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by   Iván Díez de los Ríos, et al.

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In this paper we present a memristor-inspired computational method for obtaining a type of running spectrogram or fingerprint of epileptiform activity generated by rodent hippocampal spheroids. It can be used to compute on the fly and with low computational cost an alert-level signal for epileptiform events onset. Here, we describe the computational method behind this fingerprint technique and illustrate it using epileptiform events recorded from hippocampal spheroids using a microelectrode array system.