A comparative stochastic and deterministic study of a class of epidemic dynamic models for malaria: exploring the impacts of noise on eradication and persistence of disease
share
A comparative stochastic and deterministic study of a family of SEIRS epidemic dynamic models for malaria is presented. The family type is determined by the qualitative behavior of the nonlinear incidence rates of the disease. Furthermore, the malaria models exhibit three random delays:- two of the delays represent the incubation periods of the disease inside the vector and human hosts, whereas the third delay is the period of effective natural immunity against the disease. The stochastic malaria models are improved by including the random environmental fluctuations in the disease transmission and natural death rates of humans. Insights about the effects of the delays and the noises on the malaria dynamics are gained via comparative analyses of the family of stochastic and deterministic models, and further critical examination of the significance of the intensities of the white noises in the system on (1) the existence and stability of the equilibria, and also on (2) the eradication and persistence of malaria in the human population. The basic reproduction numbers and other threshold values for malaria in the stochastic and deterministic settings are determined and compared for the cases of constant or random delays in the system. Numerical simulation results are presented.
READ FULL TEXT